Switzerland has added several new substances as directory E substances. It has also added 3 new generic statements controlling chemical space for Phenylalkylamine derivatives, Desnitazen derivatives and Orphine derivatives
Joe Bradley is a Biochemist with decades of experience in controlled drug regulations, drug discovery and cheminformatics. He has spent the last 12 years working to improve controlled drug and regulatory compliance within the chemicals and pharmaceuticals industry, through the development of software solutions which allows the rapid and accurate identification of controlled and regulated chemicals.
He founded Scitegrity in 2011 and the tools he helped create are now used by many of the worlds top chemical and pharmaceutical companies, specialist controlled drug suppliers and regulators.
He has consulted for regulators globally, helping to refine and assess the impact of proposed controlled drug regulations before final enactment.
When not absorbed in chemical regulations you'll find him on is skateboard, trials bike or with snooker cue in hand.
You can read the announcement here - although note that the Cannabinoide generic statement was already in place from earlier amendments and the Phenylalkylamine is an extension to the existing Phenylalkylamine and Benzyl phenethylamines generic statements
Phenylalkylamine : Any substance (excluding controlled substances in Schedules a, b, d and f) whose structure is derived from phenethylamine provided : – phenyl ring is unsubstituted or substituted to any extent with alkyl, alkoxy, alkylenedioxy, halogen or hydroxy substituents, whether or not further substituted in the ring by one or more other univalent substituents – the nitrogen atom of the amino group is unsubstituted or substituted with one or more alkyl or benzyl groups, regardless of whether the benzyl group is substituted or not – The alkyl chain at position R1 is unsubstituted or substituted by an alkyl group;
Desnitazen derivatives : Any substance (excluding controlled substances of Schedules a, b, d and f) whose structure is derived from desnitazene provided : – unsubstituted or substituted in any way and to any extent at the phenyl ring (R1) and at the phenyl ring of the benzimidazole (R2 ) ; – the nitrogen of the amine group can be unsubstituted or substituted to any extent with alkyl groups (R3 and R4) .
Orphine derivatives: (Piperidylbenzimidazolon e - Derivate) Any substance (excluding controlled substances in Schedules a, b, d and f) whose structure is derived from orphin e provided : – unsubstituted or substituted in any way and to any extent with alkyl, alkenyl, alkoxy, halogen, hydroxy or nitro groups on the phenyl ring (R1), on the benzimidazole structure (R2, R3) or on the piperidinyl ring (R4).
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