August 2023 Controlled Drug legislation round up


We took a break over the summer publishing our newsletter and legislation round ups. Everyone at Scitegrity hope you enjoyed your summer holidays (or winters holidays for those in the southern hemisphere)

For those who want more regular updates, all this information and much, much more is available from Controlled Substances Squared weekly legislation updates - in addition to being able to check all your chemicals regulated status whenever you want.

Below is a brief summary and highlights of some of the countries we monitor and encode in Controlled Substances Squared. The solution that allows you to easily and automatically check if your chemicals are regulated or controlled - even novel and propriatory chemicals




Due to the number and complexity of updates we can't include them all here, just a few of the highlights. Full details including all substances and legislation updates can be obtained by logging into Controlled Substances Squared at

Has added 23 as controlled substances to Table I and 3 substances are added to Table IV and in a further update another 5 substances to table I including HHC, HHC-P and HHC Acetate

Canada currently has ‘Analogues and derivatives of N-Phenyl-4-piperidinamine and its salts’ including specifically 4 named fentanyl precursors, controlled in Schedule V of the CDSA. These are being proposed to be moved into Schedule VI on 30th August 2023

A new amendment makes the following 5 additions to Schedule 2 of the Betäubungsmittelgesetz (BtMG) (Narcotics Act); ADB-BINACA, α-Pyrrolidinoisohexanophenone, Etazene, Etonitazepyne and Protonitazene

In 2 separate updates, Japan as added 5 new Designated Drugs under the Pharmaceutical and Medical Devices Act, including 4F-ABINACA, 3-CPM, etonitazepipne

The Director General of the National Agency for the Safety of Medicines and Health Products has added the following 3 substances; Hexahydrocannabinol, Hexahydrocannabinol acetate and Hexahydrocannabiphorol as controlled.While in another 2 separate updates 2-Methyl-AP-237, Etazene, Etonitazepyne, Protonitazene and Remimazolam were all added as controlled substances.

The Swedish Medicines Agency further intends to introduce an international list for seven substances as well as adding common names for six tetrahydrocannabinol isomers. These substances include HHC, HHCP, 1cp-LSD, DMXE, MXPr, MXiPr and 3-Phenylpropanoylfentanyl.

Singapore has made numerous changes to several of there generic statements controlling areas of chemical space as well as adding 14 new named substances. This represents a significant update to the Singapore regulations and chemicals considered controlled.

Seven substances have been added to the Brazilian controlled substance lists, as follows; List F1; 2-Methyl-AP-237, Etazene, Etonitazepyne and Protonitazene List F2: ADB-BUTINACA, alpha-PiHP and Isopropylbenzylamine

United States of America
The Administrator of the Drug Enforcement Administration is issuing this temporary order to schedule five synthetic benzodiazepine substances: etizolam, flualprazolam, clonazolam, flubromazolam, and diclazepam, in schedule I of the Controlled Substances Act. This temporary scheduling order is effective July 26, 2023, until July 26, 2025
It is also permanently placing metonitazen, its ethers, esters, salts and stereoisomers under control as schedule 1 substances

United Kingdom
The UK government has accepted the Advisory Council on the Misuse of Drugs (ACMD) recommendations to add Diphenidine, Ephenidine and Methoxyphenidine as schedule 2, class B drugs. It has also further responded to a 2021 proposal by the ACMD to relax research restriction with controlled drugs.

Do you want to be able to easily and automatically check if your chemicals are controlled and regulated - even for novel and propriatory chemicals - then you need Controlled Substances Squared.